comparison of intravenous and intrathecal Fentanyl injections effects in elective Cesarian

ABSTRACT

To improve painlessness quality and increasing the time of block and also for more painlessness after Cesarian surgery opiates are used in spinal anesthesia with blocker drugs in two ways intravenous and intrathecal. The main goal of this research is to make a comparison between effects of intravenous and intrathecal fentanyl injections in elective Cesarian. In this double blind clinical trial study, 50 patients who were selected for elective Cesarian surgery were divided into two equal groups, and each group received 75-100mg lidocain as a blocker agent. Then 12.5 microgram fentanyl was injected intravenously for one group and equal dose intrathecaly for the second group. Then vital signs and some side effects such as nausia, vomiting, itching and shivering were recorded for 6hours and blood pressure under 90 mmHg for 30 minutes. Results were analyzed with T test and SPSS soft ware. In this study, the time of painlessness for intrathecal fentanyl was 135.4 minutes and in intravenous group was 106.2. It was also found that in intrathecal fentanyl group and intravenous fentanyl group, blood pressure under 90mmHg was 72% and 56%, nausea 52% and 32%, vomiting 20% and 12%, and shivering 12% and 16% respectively. Itching was not seen. The average time of analgesic effect of fentanyl in intrathecal group was significantly more than the other group. Nausea, vomiting, low blood pressure and shivering were more prevalent in intrathecal group but there was no meaningful difference between them