Effects of parenteral vitamin E and selenium supplementation on immune status of dogs vaccinated with subunit and somatic antigens against taenia hydatigena
Journal of the Egyptian Society of Parasitology. 2005; 35 (2): 537-550
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| ID: emr-72350
Biblioteca responsable:
EMRO
Thirty clinically healthy dogs were divided into five equal groups; Gs 1 and 2 were vaccinated with subunit and somatic antigens [Ags] respectively in combination with vitamin E and selenium [Vit E/Se] supplement, Gs 3 and 4 were vaccinated with subunit and somatic Ags respectively and group 5 was kept unvaccinated as control positive. Dogs in the vaccinated-Vit E/Se supplemented groups had a significantly greater [P = 0.05] serum Se and alpha-tocopherol than un-supplemented Gs. Best immune response against T. hydatigena was observed in the Vit E/Se supplemented groups, as evidenced by increase production of antibody titer and IgG concentration in comparison with either vaccinated un-supplemented or control groups. Moreover, the highest protection level against T. hydatigena infection was observed in groups I and 2 [83.3%], while was 66.7% and 50% in groups 3 and 4 respectively. Subunit Ag was more efficient than somatic Ag in improving the immune status of dogs. Vit E and Se proved to be immuno-potentiating to dogs vaccinated with subunit and somatic Ags and increased the possibility for the protection against T. hydatigena infection
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Índice:
IMEMR
Asunto principal:
Selenio
/
Vitamina E
/
Ensayo de Inmunoadsorción Enzimática
/
Vacunas
/
Perros
Límite:
Animals
Idioma:
En
Revista:
J. Egypt. Soc. Parasitol.
Año:
2005