Effect of some recent analgesics on labour pain and materno-fetal blood cases and pH

ABSTRACT

This studs attempts to determine the analgesic property of nalbuphine hydrochloride, pentazocine lactate and butorphanol tartarate during labour, and their potential effects on materno-fetal blood gases and pit. The analgesic efficacy of the tested drugs was assessed by Steinhouse scoring systern [1964]. Butorphanol analgesia was superior to either nalbuphine or pentazocine in relieving labour pains. The studied analgesics caused significant maternal respiratory acidosis and fetal metabolic acidosis. These acidotic changes were more marked in the pentazocine, moderate in the nalbupitine and minimal in the butorphanol group