Outcome of different treatment options for periampullary carcinoma

To study the outcome of different treatment options for periampullary carcinoma. This study included 30 patients with periampullary carcinoma. A standard protocol was prepared for every patient comprising thorough history and full physical examination and relevant investigations. All this was recorded in data collection form. Later on outcome of different treatment options for periampullary carcinoma was discussed. All the patients were between 45-70 years. Most patients were male and belong to low socioeconomic class. The diagnosis was based on history, clinical examination and relevant investigations. The treatment options were divided into two groups. Curative resection [pancreaticoduodenectomy] was done in 18 [60%] patients. 12 [40%] patients had unresectable disease. These patients were treated by palliative procedures. Endoscopic stenting was done in 8 [66.7%] cases and 4 [33.3%] underwent surgical bypass. The morbidity noted in curative resection was [wound infection 20%, anastomotic leakage 15%, respiratory infection 10%, cholangitis 7.5% and renal failure 6.7%]. Six months survival after curative procedure was 90%. Morbidity of endocsopic stenting being blockage 20% and cholangitis in 75% of cases. Six months survival after stenting was 78%. Morbidity noted in surgical bypass included 15%[wound infection], chest infections 15% and six months survival being 75%. It was concluded that periampullary carcinoma is common in male predominantly with low socioeconomic class. Most patients were having resectable disease with relatively high morbidity