Histological changes induced by feeding on fried potato and protective role of curcumin in the liver of female rats and their offsprings

ABSTRACT

This study deals with the evaluation of the histological effect of feeding on fried potato and the protective role of curcumin on the liver of pregnant rats and their offspring. The results showed that the using of fried potato caused different histopathological lesions in the liver of female rats and their offspring. These lesions include vacuolated cytoplasm, dilated blood vessels, congested blood vessels, haemorrhage, pyknosis, necrosis and complete degenerated areas. The emerged data showed that fried potato induced histological alterations in the liver of rats similar to those caused due to acrylamide in food. The present findings suggested that curcumin have no protective effect against the degenerative effect of fried potato