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Common pitfalls in the conduct of clinical research
Medical Principles and Practice. 2006; 15 (1): 1-8
en Inglés | IMEMR | ID: emr-79502
ABSTRACT
Recently, paradigm shift from expert opinion towards evidence-based medicine has occurred encouraging physicians to base their treatment decisions on the best available research evidence. In the hierarchy of evidence randomized clinical trials [level 1 evidence] are considered of the highest quality [least biased] while non-randomized studies represent lower levels [levels 2-4]. Several pitfalls in the design and conduct of clinical research include lack of randomization, lack of concealment, lack of blinding, and errors in hypothesis testing [type I and II errors]. A basic understanding of these principles of research will empower both investigators and readers when applying the results of research to clinical practice
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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Proyectos de Investigación / Medicina Basada en la Evidencia Tipo de estudio: Ensayo Clínico Controlado / Guía de Práctica Clínica Límite: Humanos Idioma: Inglés Revista: Med. Princ. Pract. Año: 2006

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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Proyectos de Investigación / Medicina Basada en la Evidencia Tipo de estudio: Ensayo Clínico Controlado / Guía de Práctica Clínica Límite: Humanos Idioma: Inglés Revista: Med. Princ. Pract. Año: 2006