Effect of parsley on both healthy rats and those suffering from acute renal failure

ABSTRACT

The Present work was conducted to study the effect of parsley on both health rats and those suffering from acute renal failure [ARF] on the nutritional value, the relative ratio of organs to body weight, blood lipid parameters, kidney and liver functions. Thirty male albino rats [Sprague - Dawaley strain] weighting [200 +/- 5 g] divided into three main groups. The first main group [5 rats] fed on basal diet [control negative group]. The second main group [10 rats] divided to two subgroups and fed on basal diets containing 2% and 5% dried parsley. The third main group [15 rats] injected subcutaneous with glycerol [50%, W/v in saline solution] 10 ml/ kg body weight to induce acute renal failure [ARF] and divided into three subgroups, the first fed on basal diet as a [control positive], while second and third subgroups fed on basal diet containing 2% and 5% dried parsley, respectively. The result revealed that, feeding rats, which suffering from ARF on basal diet containing dried parsley [2% and 5%] resulted in improvement on the nutritional value as well as healthy groups, organs weight/body weight relative ratio, serum cholesterol, triglycerides, low density lipoprotein cholesterol [LDL-c], high density lipoprotein cholesterol [HDL-c], very low density lipoprotein cholesterol [VLDL-c], uric acid, urea nitrogen, aspartate amino transferase [AST] and alanine amino transferase [ALT] than the control positive group. It was concluded that parsley at high concentration 5% realized the best effect on lipid profile, kidney and liver functions