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Molecular basic of breast cancer
Saudi Medical Journal. 2006; 27 (1): 9-16
en Inglés | IMEMR | ID: emr-80560
ABSTRACT
Breast cancer is the most frequent cancer in women and represents the second leading cause of cancer death among women after lung cancer. A common phenotypic abnormality of breast cancer cells is dysregulation of cell cycle control. The transformation of normal cell to a cancer cell appears to depend on mutation in genes that normally control cell cycle progression, thus leading to loss of the regulatory cell growth. We summarize here the molecular regulation of mammary carcinoma with regards to the most prominent oncogenes and tumor suppressor genes and their outcome in terms of cellular prognosis, and tumor development
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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Oncogenes / Neoplasias de la Mama / Marcadores Genéticos / Pruebas Genéticas / Genes Supresores de Tumor / Medición de Riesgo / Biología Molecular / Mutación Límite: Femenino / Humanos Idioma: Inglés Revista: Saudi Med. J. Año: 2006

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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Oncogenes / Neoplasias de la Mama / Marcadores Genéticos / Pruebas Genéticas / Genes Supresores de Tumor / Medición de Riesgo / Biología Molecular / Mutación Límite: Femenino / Humanos Idioma: Inglés Revista: Saudi Med. J. Año: 2006