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biochemical properties of actinobacillus actinomycetemcomitans[Aa] and their effects on cell-mediated immunity in periodontally affected patients
Al-Azhar Dental Journal. 1987; 2 (2): 191-205
en Inglés | IMEMR | ID: emr-8290
ABSTRACT
Lymphocytes were cultured from patients with chronic gingivitis, marginal periodontitis and from matched healthy subjects. Lymphocyte transformation was significantly suppressed by all the examined As Strains [9710, 109, in a dose dependent fashion. Aa-immunosuppression was due to direct toxic effects on lymphocytes. The suppressive factor is heatstable, endotoxic and non-specific [due to effect on PPD]. The data presented in this paper support the claim that, the increase in severity of periodontal disease corresponded to a marked decrease in cell-mediated immune responses to bacterial antigens. Subsequently, the suppression of cellular immunity in subjects with starting periodontal trouble could be considered as a warning signal of the progression of the disease to its severe form
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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Técnicas In Vitro / Infecciones por Actinobacillus / Terapia de Inmunosupresión / Inmunidad Celular Idioma: Inglés Revista: Al-Azhar Dent. J. Año: 1987

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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Técnicas In Vitro / Infecciones por Actinobacillus / Terapia de Inmunosupresión / Inmunidad Celular Idioma: Inglés Revista: Al-Azhar Dent. J. Año: 1987