use of proteolytic enzyme therapy in oral surgery

ABSTRACT

1- The use of proteolytic enzymes trypsin and chemotrypsin enhances the healing process of jaw fracture and significantly reduced the degree or both post-traumatic and post-operative edema when used in different cases of fractures of the facial skeleton. 2- To achieve satisfactory healing of cysts, the authors recommend treatment by enucleation, together with reduction of the size of cyst cavity by cutting away expanded cortical plate of bone and putting in mattress surfaces. At the same time, the patient should be given prophylactic antibiotic therapy and proteolytic enzymes. 3- Trismus and pain suffered by a patient who has undergone surgery for removal of lower third molars can be considerable reduced by the use of proteolytic enzyme therapy. 4- The types of bacteria giving rise to odontogenic or non odontogenic cervicofacial abscesses have been defined in this study into, streptococci and staphylococci. Streptococcal infection is best treated by ampicillin or erythromycin. For staphylococcal and gram negative infection cotrimoxazole, erythromycin or a cephalosporin, where no differentiation is possible or mixed bacteria is present erythromycin is the first choice. Accordingly the proper selection of antibiotic, proper drainage together with proteolytic enzyme therapy which was found to be effective in the rapid debridement of the abscesses, is our recommended line of treatment of all cervicofacial abscess