Frequency of transitional cell carcinoma in local suburban population of Karachi

ABSTRACT

To determine the clinicopathological characteristics and frequency of different pathological lesions, particularly Transitional Cell Carcinoma in urinary bladder biopsies, this study was conducted in histopathology section of tertiary care hospitals [Jinnah and Civil hospital] filtering the suburban population of Karachi during August 2001 to July 2005. All patients who visited the Urology. Out Patient Department and presented with haematuria, dysuria etc. were included. Cystoscopy and bladder biopsies were performed. The biopsies were preserved in 10% formalin. Gross examination was done and embedded in paraffin. Light microscopy technique was used for diagnosis. Out of 43 patients, 31 [72.09%] were males and 12 [27.90%] were females. The spectrum of pathological lesions included inflammations, dysplasia and tumours. Transitional cell carcinoma was the most common tumour seen in this study; [93.33%] cases. The peak age of incidence was between 41-68 years