[Serum lipids in patients with mixed anxiety depressive disorder]

ABSTRACT

Psychiatric disorders especially depression has known association with coronary artery disease but the relationship with other psychological conditions still obscure. To evaluate the lipids profile in patients with anxiety and depressive disorder. This cross-sectional study was performed on 100 patients arranged in four groups using random sampling. Group 1 [25 patients] with major depressive disorder; group 2 [25 patients] with generalized anxiety disorder; group 3 [25 patients] with mixed anxiety and depression; and group 4 [25 patients] as control group. Data was collected using a questionnaire including demographic information, past history of patient, and also Beck and Kettel questionnaire. Blood samples were collected to measure total cholesterol, triglycerides, HDL and LDL-C. The data were analyzed using SPSS10 and t-test, X[2], and ANOVA tests. Out of 100 patients, 75% were females. Means of TC [226.75 +/- 45.35], TG [189.37 +/- 69.84], HDL-C [45.51 +/- 10/48] and LDL-C [150.35 +/- 36.65] were higher in mixed anxiety depressive disorder. Regarding the data obtained in our study, high lipid levels were found in mixed anxiety depressive disorder. To reduce the chance of atherosclerosis, measurement of lipids level in such patients is recommended