Relationship between helicobacter pylori immunoglobulin G antibody and thrombotic ischemic stroke

ABSTRACT

Several studies have assessed association between Helicobacter pylori infection and thrombotic ischemic stroke. This study was designed to investigate the association between this organism and ischemic strokes. Antibody against H. pylori [Hp IgG] was measured in 81 patients with stroke and 43 subjects without stroke. Hp IgG titer more than 20 u/ml was defined as positive. Hp IgG seropositivity was found in 67.4% of control subjects and 70.4% of cases [P = 0.838]. The means of serum Hp IgG titers in control subjects and cases were 51.1859 u/ml and 50.1641 u/ml, respectively [P = 0.927]. The difference between these 2 groups was not significant statistically. There wasn't any significant difference in seropositivity of Hp IgG between case and control subjects in men and women. It seems that H. pylori IgG titer hasn't a predictive role for thrombotic ischemic stroke