Antilithiatic activity of leaves of Dalbergia rubiginosa Roxb

ABSTRACT

Renal calculus is a common and recurrent problem occurring in about 4% of the world population. The traditional system of Indian medicine suggests several herbs against lithiasis. One such plant is Dalbergia rubiginosa Roxb. which belongs to the family Leguminosae. The effect of alcoholic and aqueous extracts of the leaves of Dalbergia rubiginosa Roxb. [DRL] against lithiasis induced by 1% glycolated water for 35 days in male Wistar rats was tested in this study. Rats were fed with ethylene glycol [1%] mixed with drinking water for 35 days. Simultaneous treatment with the extracts of DRL considerably reduced the urinary risk parameters such as calcium, oxalate, phosphate, proteins and raised magnesium. These observations lead to the conclusion that the extracts are effective against Iithiasis. Phytochemical analysis of alcoholic and aqueous extracts of the leaves was also carried out