Osteoporosis in postmenopausal diabetic women; prevalence and related factors
Iranian Journal of Nuclear Medicine. 2008; 16 (2): 28-33
en Inglés
| IMEMR
| ID: emr-87082
ABSTRACT
Diabetes mellitus and osteoporosis are two frequent medical conditions with an increasing prevalence in elderly. This study is conducted to evaluate osteoporosis in postmenopausal females with type 2 diabetes mellitus in Sanandaj, the provincial center of Kurdistan province in the west of Iran. From an initial population of 2500 women with type 2 diabetes, 242 postmenopausal women were randomly selected and were compared with 221 non-diabetic postmenopausal women, matched by age and body mass index [BMI]. Bone mineral density [BMD] was measured at the L2-L4 vertebrae [anteroposterior projection] and femoral neck with dual energy X-ray absorptiometry [DXA]. The statistical significance was set at a P value of .05 or lower. Prevalence of femoral neck osteoporosis in diabetic women was 30.2 percent [73 cases] and osteopenia was 48.3 percent [117 cases]. Osteoporosis prevalence in spine was 7.9 percent [19 cases] and ostropenia was 46.3 percent [112 cases]. Osteoporosis in both femoral neck [P=0.001] and spine [P=0.04] were significantly higher in patients than in controls. Correlation between HbA1c and femoral neck [p=0.11, correlation coefficient=0.04] and also spine [p=0.10, correlation coefficient= -0.12] T score was not significant. No significant correlation was found between osteoporosis with presence of microalbuminuria [P=0.91], retinopathy [P=0.33], hypertension [P=0.70], ischemic heart disease [P=0.57] and insulin therapy [P=0.08]. This study shows that type 2 diabetic patients have significantly lower T score values and more frequency of osteoporosis than healthy postmenopausal women
Buscar en Google
Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Distribución Aleatoria
/
Absorciometría de Fotón
/
Densidad Ósea
/
Prevalencia
/
Posmenopausia
/
Diabetes Mellitus Tipo 2
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio de prevalencia
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Iran. J. Nucl. Med.
Año:
2008
Similares
MEDLINE
...
LILACS
LIS