frequency of coagulase negative staphylococci urinary infections with antimicrobial resistance pattern in Rafsanjan

ABSTRACT

Coagulase negative staphylococci are recognized as the important agents in the urinary infections of young women and elderly men. These agents are resistant to many of the antibiotics. The objective of this study was to find out the frequency and antimicrobial resistance pattern of this organism in urinary infections. This cross sectional study was performed on 1067 patients who were referred to Rafsanjan laboratory due to urinary symptoms. Urine analysis and cultures with [Blood agar, Eosin methylen blue, Hinton Agar], besides Catalase and coagulase assay were done. Coagulase negative staphylococci was isolated from 6% of cultures. Frequency of this infection had no difference between female and male and also between different groups. Based on antibiotic resistance pattern; resistance to Cefalotin was [72.5%], Cotrimoxazole [62.5%], Penicillin [60%], Nitrofurantoin and Gentamycin [55%], Nalidixic acid [52.5%], Oxacillin [47.5%, Cephalexin [45%], Clindamycin [35%], Vancomycin [30%] and Ciprofloxacin [2.5%]. Positive cultures are significant [6%] and recognition of urinary infection due to Coagulase negative staphylococci is very important because misdiagnosis leads to wrong treatment