Testosterone assay before and after hemodialysis in chronic renal failure

ABSTRACT

Estimation of plasma testosterone with radioimmunoassay technique was done in eleven patients suffering from chronic renal failure both before and after the performance of haemodialysis. Low testosterone level was found before the dialysis while normal level was detected after the performance of the dialysis. Hypotestosteronemia could partly explain the presence of impotence, while normal level after the dialysis indicates the participation of other parameters. Diminished response of the Leydig cells to produce testosterone in chronic renal failure is suggested as a sequels of the effect of the uremic toxins