Potential antimicrobial activity of some complexed tetracyclines

ABSTRACT

Cobalt, nickel, copper and zinc complexes of tetracvcline class of antibiotics such as oxytetracyline, tetrabid, vibramycine and chlortetracycline have been synthesised and tested against bacterial species staphylococcous pseudomonas aeruginosa and klebsella, pneumonae. The screening studies significantly show that the metal complexes of these antibacterial have more potent antibacterial effect than the simple uncomplexed tetracycline