Comparative study on chemical composition and antimicrobial activity of Egyptian and Canadian propolis

Two propolis samples from Egypt and Canada were investigated by GC/MS, 103 compounds were identified. mainly terpenoids and phenolics. 17 being new for propolis. The samples showed some similarities in their qualitative composition of the phenolics. In Canadian propolis benzoic acid, trans-p-coumaric acid, benzyl-trans-4-coumarate and pinocembrin were predominant. The Egyptian propolis showed the presence of 7 di-and triterpenoids. from which three are new. The antimicrobial activity of propolis collected from Egyptian propolis showed the highest antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli, Salmonella typhi, .Asprgillus flavus; Asprgillus fumigatus; Mucor and Candida albicans, while Canadian propolis has the highest activity against Staphylococcus aureus: Bacillus subtitlis; Erwinia carotovora; Asprgillus ochraceus and Asprgillus niger