Synthesis of some novel analogues of 4-[l-pyrrolidinyl] piperidine and their effect on plasma glucose level
Pakistan Journal of Pharmaceutical Sciences. 2010; 23 (2): 220-223
en Inglés
| IMEMR
| ID: emr-98358
ABSTRACT
In the present study some compounds of 4-[1-Pyrrolidinyl] Piperidine [I] have been synthesized. Structures of compounds were confirmed by using HNMR, IR, Mass and UV spectrophotometer techniques. All the derivatives [II, III, IV and V] and the parent compound [I] at the dose of 100 mg/kg were evaluated for their effect on plasma glucose level. Compound [II] was the only derivative which showed effect on plasma glucose level
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Piperidinas
/
Glucemia
/
Ratas Sprague-Dawley
/
Hipoglucemiantes
Límite:
Animales
Idioma:
Inglés
Revista:
Pak. J. Pharm. Sci.
Año:
2010
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