Identification and quantitative determination of 4-hydroxyisoleucine in trigonella foenum-graecum L. from Iran
Journal of Medicinal Plants. 2010; 9 (Supp. 6): 29-34
en Inglés
| IMEMR
| ID: emr-98656
ABSTRACT
The seeds of Trigonella foenum-graecum L. [Fenugreek] are used in Iranian traditional medicine as blood sugar lowering agent. According to last investigations, hypoglycemic property is related to the amino acids of the plant specially 4-hydroxyisoleucine. In this research, identification and quantitative determination of 4-hydroxyisoleucine in Fenugreek seeds from Shahreza, central part of Iran, has been investigated. Methods:
Powdered seeds of the plant were defatted and then extracted by using ethanol 50%. In order to isolation of 4-hydroxyisoleucine from the extract, ion exchange chromatography was used and the amino acid content was determined by using high performance liquid chromatography technique. The results showed the presence of 0.4% 4-hydroxyisoleucine in the plant seeds which is considerable amount of the amino acid in the plant collected from Iran. According to the effects of 4-hydroxyisoleucine such as antihyperglycemic and antihyperlipidemic properties, fenugreek can be considered as an herbal remedy in supportive treatment of these disorders
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Semillas
/
Extractos Vegetales
/
Cromatografía Líquida de Alta Presión
/
Cromatografía por Intercambio Iónico
/
Aminoácidos
/
Isoleucina
/
Hipolipemiantes
Idioma:
Inglés
Revista:
J. Med. Plants
Año:
2010
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