Resultados de las reacciones serológicas en pacientes con diagnóstico presuntivo de toxoplasmosis / Results of serological reactions in patients with presumptive diagnosis of toxoplasmosis

ABSTRACT

Eventhough Toxoplasma gondii is an ubiquitous parasite that can affect most of human estructures and organs, not all clinical manifestations suggestive of being produced by it are caused by this protozoon. For these reasons sera samples of patients suspected of having toxoplasmosis are sent to the laboratory for detecting specific antibodies which would facilitate the differential diagnosis. Thus, 716 sera from suspected patients, mainly from the Metropolitan Region of Chile, were sent to the Parasitology Laboratory of Chile University in order to carry out in them, specific serological tests for toxoplasmosis indirect hemagglutination test (IHAT), Sabin Feldman reaction (SFT) and complement fixation test (CFT). Were considered positive IHAR and/or SFT with titers * 1 16 and CFT with titer * 1 5. The pathologies for demanding these serological tests were obstetrical probelmas 210 (29,3%), congenital problems 193(27,0%), ophthalmopathies 81(11.3%), adenopathies 77(10.8%), AIDS 67(9.4%), miocardiopathies 46(6.4%) and miscellaneous 42(5.9%). The positivity found in these sera was higher in ophthalmopathies (61.7%), followed by obtetrical problems, miscellaneous problems, miocardiopathies and AIDS (50.7-52.4%), less frequent was the positivity in adenopathies (35.1%) and congenital problems (23.1%). In general, the 43.7% of positivity for toxoplasmosis found in these patients is higher than the 37.0% found in the general population. High titers of IHAT and SFT plus positive CFT was found in 13-fold higher proportion than in the general population