Host tissue destruction by Entamoeba histolytica: molecules mediating adhesion, cytolysis, and proteolysis
Mem. Inst. Oswaldo Cruz
;
87(supl.5): 57-60, 1992.
Artículo
en Inglés
| LILACS
| ID: lil-128420
ABSTRACT
Entamoeba histolytica, the protozoan parasite causing human amoebisis, has recently been found to comprise two genetically distinct forms, potentially pathogenic and constitutively nonpathogenic ones. Host tissue destruction by pathogenic forms is belived to result from cell functions mediaed by a lectin-type adherence receptor, a pore-forming peptide involved in host cell lysis, and abundant expression of cysteine proteinase(s). Isolation and molecular cloning of these amoeba products have provided the tools for structural analyses and manipulations of cell functions including comparisons between pathogenic and nonpathogenic forms
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Entamoeba
/
Entamoeba histolytica
/
Entamebiasis
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
1992
Tipo del documento:
Artículo
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