Nephrotic syndrome associated with hepatointestinal schistosomiasis
Rev. Inst. Med. Trop. Säo Paulo
; 34(4): 273-6, jul.-ago. 1992. tab
Article
en En
| LILACS
| ID: lil-134517
Biblioteca responsable:
BR66.1
ABSTRACT
Schistosomal nephropathy has long been related to the hepatosplenic form of schistosomiasis. In the last few years, 24 patients with hepatointestinal schistosomiasis and the nephrotic syndrome were studied. Aiming at evaluating a possible etiologic participation of schistosomiasis in the development of the nephropathy, this group was comparatively studied with a group of 37 patients with idiopathic nephrotic syndrome. Both groups had a different distribution of the histologic lesions. In the group with schistosomiasis there was a statistically significant prevalence of proliferative mesangial glomerulonephritis (33.3%), whereas in the control group there was prevalence of membranous glomerulonephritis (32.4%). On immunofluorescence, IgM was positive in 94.4% of the patients with schistosomiasis versus 55.0% in the control group (P < 0.01). In the group with schistosomiasis, 8 patients evidenced mesangial proliferative glomerulonephritis and 5, membranoproliferative glomerulonephritis. In both histological types immunofluorescence showed IgM and C3 granular deposits in the glomeruli. The data in this study suggests that mesangial proliferative and membranoproliferative glomerulonephritis, with glomerular granular IgM and C3 deposits, represent the renal lesions of the schistosomiasis associated nephropathy
Texto completo:
1
Índice:
LILACS
Asunto principal:
Esquistosomiasis mansoni
/
Hepatomegalia
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Síndrome Nefrótico
Tipo de estudio:
Risk_factors_studies
Límite:
Female
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Humans
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Male
Idioma:
En
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Asunto de la revista:
MEDICINA TROPICAL
Año:
1992
Tipo del documento:
Article