A comparative study of resistance to MHV3 infection in genetically homogeneous and heterogeneous mouse populations
Braz. j. med. biol. res
; 25(10): 1025-7, 1992. tab, graf
Article
en En
| LILACS
| ID: lil-134646
Biblioteca responsable:
BR26.1
RESUMO
Resistance to MHV3 infection was investigated in genetically homogeneous inbred (A/J, BALB/c) and genetically selected (High, Low) mouse lines. The A/J and L lines are resistant and the BALB/c and H mice are susceptible. The genetic analysis was performed on the F1 hybrids, as well as on the genetically heterogeneous F2 populations and backcrosses bred from HxL and A/JxBALB/c lines. The mortality rates of the F1 hybrids showed codominance of susceptibility and resistance characters. The results indicate that the same MHV3 susceptibility genes are present in isogenic and selected lines and corroborate previous results showing that at least two major genes are involved in the control of this response
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Índice:
LILACS
Asunto principal:
Infecciones por Coronavirus
/
Virus de la Hepatitis Murina
/
Hepatitis Viral Animal
Límite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
1992
Tipo del documento:
Article
/
Congress and conference