Utilizaçäo terapêutica do interferon-gama em doença granulomatosa crônica: fundamentos, efeitos sobre a síntese de reativos intermediários do nitrogênio e outros possíveis mecanismos de açäo / Therapeutic use of the gamma-interferon in a chronic granulomatous disease: basis, effects on the synthesis of intermediary reactives of nitrogen and other possible mechanisms of action
Rev. bras. alergia imunopatol
;
18(3): 108-17, maio-jun.1995. ilus, tab
Artículo
en Portugués
| LILACS
| ID: lil-154259
ABSTRACT
Therapy with rIFN-ç did not cause an induction of NO synthesis by neutrophils or mononuclear cells from CGD patients, nor changed any of the immunological parameters of these patients. These results indicate that O2- production is not essential for NO synthesis in human leukocytes and that therapy with rIFN-ç in CGD patients does not induces NO synthesis by their leucocytes. The mechanisms by which rIFN-ç therapy produces clinical improvement remain to be investigated
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Índice:
LILACS (Américas)
Asunto principal:
Interferón gamma
/
Enfermedad Granulomatosa Crónica
Límite:
Humanos
Idioma:
Portugués
Revista:
Rev. bras. alergia imunopatol
Asunto de la revista:
Alergia e Inmunología
Año:
1995
Tipo del documento:
Artículo
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