Antagonismo do flumazenil ao flunitrazepam / Flunitrazepam with flumazenil
Rev. bras. anestesiol
;
43(5): 297-302, set.-out. 1993. ilus, tab
Artículo
en Portugués
| LILACS
| ID: lil-159139
ABSTRACT
Flumazenil is a competitive inhibitor of the specific biding of benzodiazepines to central nervous system receptor sites and it is valuable in reversing their sedative effect. Twenty-four healthy patients (ASA I and II), both male and female, with age between 19 and 58 years and weight between 46 and 79 kg, scheduled for elective surgery under flunitrazepam oral premedication and intravenous sedation after spinal anesthesia, were submitted to a trial with flumazenil for reversal of sedation. Judged by the degree of sedaation, comprehension, cooperation and time and space orientation, flumazenil showed good results. Only 12 por cent of the patients presented resedation after 120 minutes. No adverse effect was observed.
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Índice:
LILACS (Américas)
Asunto principal:
Periodo de Recuperación de la Anestesia
/
Flumazenil
/
Flunitrazepam
/
Anestesia Epidural
Límite:
Adulto
/
Humanos
Idioma:
Portugués
Revista:
Rev. bras. anestesiol
Asunto de la revista:
Anestesiología
Año:
1993
Tipo del documento:
Artículo
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