Efecto de un extracto seco de boldo sobre el tránsito intestinal oro-cecal en voluntarios sanos / Effect of a dry boldo extract on oro cecal intestinal transit time in healthy volunteers
Rev. méd. Chile
;
123(8): 955-60, ago. 1995. ilus
Artículo
en Español
| LILACS
| ID: lil-162297
RESUMO
Background:
Boldo (peumus boldus Molina) is a widely used medicinal plant. However, its physiological effects are not well known. Recent studies in animals showed that certain components of boldo relax smooth muscle and prolong intestinal transit.Aim:
to assess the effects of a dry boldo extract on oro cecal transit time in normal humans. Subjects andmethods:
twelve volunteers received 2.5 g of a dry boldo extract or a placebo (glucose) during 2 successive periods of 4 days. On the fourth day, 20 g of lactulose were administered and breath hydrogen was collected every 15 min. Oro cecal transit time was defined as the time in which breath hydrogen increased by 20 ppm over the fasting level.Results:
oro cecal transit time was larger after dry boldo extract administration, compared to placebo (112.5ñ15.4 and 87ñ11.8 min respectively, paired t p<0.05).Conclusions:
dry boldo extract prolongs oro cecal transit time, a possible explanation for its medicinal use
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Índice:
LILACS (Américas)
Asunto principal:
Plantas Medicinales
/
Peumus
/
Motilidad Gastrointestinal
Tipo de estudio:
Ensayo Clínico Controlado
/
Guía de Práctica Clínica
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
1995
Tipo del documento:
Artículo
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