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Multidrug resistant tuberculosis outbreak in Buenos Aires: DNA fingerprinting analysis of isolates
Medicina (B.Aires) ; 56(1): 45-7, ene.-feb. 1996. tab, graf
Artículo en Inglés | LILACS | ID: lil-163383
RESUMO
In order to determine the possible relationship among HIV patients coinfected with multidrug resistant tuberculosis strains who had been receiving clinical assistance in our Hospital, clinical and epidemiological information from 28 patients was collected. DNA fingerprinting by restriction fragment length polymorphism (RFLP) pattern was performed on the mycobacterial isolates from these patients, using the restriction enzyme Pvull and IS 6110 as genetic marker. A unique RFLP pattern was found in 10 isolates from 10 different patients who had a disease caused by a single strain. Our findings confirm RFLP as a reliable and useful tool to analyze TB transmission.
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Índice: LILACS (Américas) Asunto principal: Tuberculosis Pulmonar / Brotes de Enfermedades / Dermatoglifia del ADN / Tuberculosis Resistente a Múltiples Medicamentos Límite: Adulto / Femenino / Humanos / Masculino Idioma: Inglés Revista: Medicina (B.Aires) Asunto de la revista: Medicina Año: 1996 Tipo del documento: Artículo

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Índice: LILACS (Américas) Asunto principal: Tuberculosis Pulmonar / Brotes de Enfermedades / Dermatoglifia del ADN / Tuberculosis Resistente a Múltiples Medicamentos Límite: Adulto / Femenino / Humanos / Masculino Idioma: Inglés Revista: Medicina (B.Aires) Asunto de la revista: Medicina Año: 1996 Tipo del documento: Artículo