Evaluation of a direct immunofluorescent antibody (Difma) test using Leishmania genus specific monoclonal antibody in the routine diagnosis of cutaneous leishmaniasis
Rev. Soc. Bras. Med. Trop
;
28(2): 99-103, abr.-jun. 1995. tab
Artículo
en Inglés
| LILACS
| ID: lil-163751
ABSTRACT
A direct immunofluorescent antibody (DIFMA) test using a Leishmania genus-specific monoclonal antibody was evaluated in the routine diagnosis of cutaneous leishmaniasis (CL) in Ecuador. This test was compared with the standard diagnostic techniques of scrapings, culture and histology. Diagnostic samples were taken from a total of 90 active dermal ulcers from patients from areas of Ecuador known to be endemic for cutaneous leishmaniasis. DIFMA was positive in all lesions. It was shown to by significantly superior to standard diagnostic methods either alone or in combination. The sensitivity of DIFMA did not diminish with chronicity of lesions. This test proved to be extremely useful in the routine diagnosis of CL because it is highly sensitive, is easy to use and produces rapid results.
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Índice:
LILACS (Américas)
Asunto principal:
Anticuerpos Antiprotozoarios
/
Leishmaniasis Cutánea
/
Leishmania
/
Anticuerpos Monoclonales
/
Especificidad de Anticuerpos
Tipo de estudio:
Estudio diagnóstico
Límite:
Animales
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Ecuador
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
1995
Tipo del documento:
Artículo
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