Your browser doesn't support javascript.
loading
Use of the 2,3-diacyl-trehalose and the purified protein derivative in the serodiagnosis of tuberculosis in AIDS
Mem. Inst. Oswaldo Cruz ; 91(1): 97-100, Jan.-Feb. 1996. tab
Artículo en Inglés | LILACS | ID: lil-164143
ABSTRACT
The effect of the human immunodeficiency virus (HIV) infection on IgG production against purified protein derivative (PPD) and 2,3-diacil-trehalose (SL-IV) was investigated by an enzyme-linked immunosorbent assay (ELISA) test. Comparison between the antigens showed that immunocompetent patients produce preferentially antibodies to SL-IV than to PPD (73.3 por cento versus 63.3 por cento). Combination of the these results showed an increase of the sensitivity to 80 por cento, which decreased over the spectrum of immunodepression caused by HIV. In the tuberculous HIV seropositive group the sensitivities of SL-IV and PPD were 36.4 por cento versus 40 por cento and 0 por cento versus 22.2 por cento in the tuberculosis/acquired immunodeficiency syndrome (TB/AIDS) group. Combination of these results gave respectively 54.5 por cento and 20 por cento, showing that serological tests have limited value for diagnosis of tuberculosis in HIV infected patients. High antibody levels were observed in HIV seropositive asymptomatic group, but only two individuals were positive for both antigens. In the follow up, one of them tuberculous lymphadenitis, indicating that further work is needed to access the value of serological tests in predicting tuberculosis in HIV infected individuals.
Asunto(s)
Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Tuberculosis / Proteínas / Síndrome de Inmunodeficiencia Adquirida Tipo de estudio: Estudio pronóstico Límite: Humanos Idioma: Inglés Revista: Mem. Inst. Oswaldo Cruz Asunto de la revista: Medicina Tropical / Parasitología Año: 1996 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Tuberculosis / Proteínas / Síndrome de Inmunodeficiencia Adquirida Tipo de estudio: Estudio pronóstico Límite: Humanos Idioma: Inglés Revista: Mem. Inst. Oswaldo Cruz Asunto de la revista: Medicina Tropical / Parasitología Año: 1996 Tipo del documento: Artículo