Terapia génica: ficcion o realidad / Gene therapy: fact or fantasy
Rev. méd. Chile
;
124(2): 237-47, feb. 1996.
Artículo
en Español
| LILACS
| ID: lil-173327
ABSTRACT
The great advances in molecular biology have encouraged the treatment of diseases through gene intervention. According to present knowledge, all diseases somehow have their origin or are related to genes. Different stages must be overcome to intervene in genes a) Identification of the genes to intervene. Methodologies have been developed and a number of genes identified b) Codification of its structure. The technology for this purpose is already know and the process had been automated c) Locate the adequate vector that, without damaging the cell, is capable to introduce in nucleus the genetic material. There are many studied alternatives. However the ideal vector, that would select the target cells, be risk-free and guarantee prolonged results, has not been found yet d) To achiev the gene expression, codifying the respective protein or its inhibition, according to the case. Some success has been obtained in this field, but technology has to be improved to obtain a uniform and satisfactory response. Advances achieved in the last years have been impressive and technologies will presumably continue to improve
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Índice:
LILACS (Américas)
Asunto principal:
Ingeniería Genética
Límite:
Humanos
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
1996
Tipo del documento:
Artículo
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