Prevention of preeclampsia with calcium supplementation and its relation with L-arginine: citric oxide pathway
Braz. j. med. biol. res
;
29(6): 731-41, jun. 1996. tab
Artículo
en Inglés
| LILACS
| ID: lil-181407
ABSTRACT
Pregnancy-induced hypertension (PIH) remains a common cause of maternal and fetal morbidity and mortality. During the past 7 years, some progress has been made in the prevention of PIH. Specifically, clinical studies have shown that supplementation with calcium can significantly reduce the frequency of PIH, especially in populations with a low calcium intake. We have suggested that, in such a population, calcium supplementation is a safe and effective measure for reducing the incidence of PIH. Calcium supplementation reduces the risk of PIH by maintaining the serum ionized calcium level which is crucial for the production of endothelial nitric oxide, the increased generation of which maintains the vasodilatation that is characteristic of normal pregnancy. In PIH there is an impaired nitric oxide synthesis and cyclic GMP production.
Buscar en Google
Índice:
LILACS (Américas)
Asunto principal:
Preeclampsia
/
Complicaciones Cardiovasculares del Embarazo
/
Alimentos Fortificados
/
Calcio
/
Hipertensión
Límite:
Femenino
/
Humanos
/
Embarazo
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1996
Tipo del documento:
Artículo
/
Congreso y conferencia
Similares
MEDLINE
...
LILACS
LIS