HTLV-I/II as a common etiology of myelopathies in Bahia, Brazil
Braz. j. med. biol. res
;
29(6): 757-61, jun. 1996. tab
Artículo
en Inglés
| LILACS
| ID: lil-181409
RESUMO
Infection by human T-cell lymphotrophic virus type I (HTLV-I) is associated with a myelopathy known as tropical spastic paraparesis (TSP). The prevalence of HTLV-I infection was found to be high in a pilot study in Bahia, Brazil. In the present study, among patients with myleopathy of unclear etiology, 27 per cent (17/62) were immunoblot reactive to HTLV-I/II (serum and CSF), but none of 40 consecutive patients seen at the neurological clinic and having a well-established neurological diagnosis had detectable antibodies against those viruses (discrimination between HTLV-I and HTLV-II was not possible with the tests we used). The clinical syndrome of typical TSP with upper limb hyperreflexia was found to be a significant feature among the HTLV-I/II-seropositive patients compared to seronegative individuals. The 17 HTLV-I/II-reactive individuals had negative tests for syphilis, toxoplasmosis and schistosomiasis. TSP was also associated with female gender (P=0.001). We conclude that TSP is strongly associated with HTLV-I/II infection in women in Bahia.
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Índice:
LILACS (Américas)
Asunto principal:
Enfermedades de la Médula Espinal
/
Infecciones por HTLV-I
/
Infecciones por HTLV-II
/
Paraparesia Espástica Tropical
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1996
Tipo del documento:
Artículo
/
Documento de proyecto
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