Factores de urovirulencia bacteriana: asociación con recurrencias y anomalías anatómicas y funcionales en niños con infección del tracto urinario / Urinary bacterial virulence factors: association with recurrence of anatomical and functional abnormalities and urinary tract infection in children

ABSTRACT

A prospective sample of children was incorporated into a followup protocol after their first episode of bacteriologically-demonstrated urinary tract infection. In all patients an abdominal ultrasound examination and a mictional urethrocystography were done and the presence of fiambriae was studied in isolated strains of Escherichia coli. Two hundred fifteen cases had an adequate adherence to the study protocol, 190 caused by E coli. Fiambristed E coli strains were isolated with greater frequency from children with pyelonephritis than from those with a low urinary tract infection (50 and 28 percent respectively). The absence of fiambriae in E coli strains was associated with a higher risk of recurrent infections (odds ratio=3, confidence intervals=1.1-10.2). These data are consistent with foreign reports and support the need to study adhesins in E coli strains isolated from children with urinary tract infections