Effects of Goyazensolide during in vitro cultivation of Schistosoma mansoni
Mem. Inst. Oswaldo Cruz
;
92(3): 427-9, May-Jun. 1997. graf
Artículo
en Inglés
| LILACS
| ID: lil-189319
RESUMO
Goyazensolide, a component extracted of Eremanthus goyazensis showed a significant inhibitory effect on egg-laying of Schistosoma mansoni during in vitro cultivation of this parasite. Motility of the worms was also reduced under treatment with goyazensolide and 90 per cent of mortality was reached with concentration up to 4 µg/ml. It has found that separated worms were more susceptible than worms pairing during drug exposition and female alone was significantly more susceptible than male worm in the same conditions of in vitro cultivation. Natural products isolated from plants represent potencial sources for the identification of structures useful for the design of alternative molecules to be used as new drug substances against several infectious deseases.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Plantas Medicinales
/
Schistosoma mansoni
/
Técnicas In Vitro
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
1997
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS