Edema pulmonar agudo asociado a hidroclorotiazida / Acute pulmonary edema associated to hydrochlorotiazide

ABSTRACT

Hydrochlorotiazide may cause pulmonary edema. We report 2 female patients aged 58 and 69 years old, who after the ingestion of this diuretic, were admitted to an intensive care unit with fever, digestive symptoms, severe dyspnea, hypotension and a hemodynamic pattern resembling hypovolemia. Both had a good response to volume repletion and vasoactive drugs. Despite the severity of the clinical picture, they had a full and fast recovery. This type of reaction to hydrochlorotiazide is probably idiosyncratic and must be considered in the differential diagnosis of pulmonary edema