E-test para determinar concentraciones inhibitorias mínimas, estimar la diversidad bacteriana e identificar presuntivamente beta-lactamasas en cepas de pseudomonas aeruginosa y acinetobacter baumanii asociadas a infecciones intrahospitalarias / E-test to study minimal inhibitory concentrations, bacterial diversity and to presumably identify beta-lactamases in pseudomonas aeruginosa and acinetobacter baumanii strains associated to intrahospitaly infections

ABSTRACT

Sixty eight strains of Pseudomonas Aeruginosa and acinetobacter baumanii isolated on a teaching hospital were analized with E-test strips to determine their minimal inhibitory concentration for different antimicrobials. More than 75 percent of Acinetobacter baumanii were resistent to Piperacillin, Cefpirome, Cefepime, Gentamicin or Amikacin, 40 percent of strains were resistant to Ceftazidime, 27 and 53 percent of isolates had a decreased susceptibility to Meropenem and Piperacillin-tazobactam respectively. Twenty eight to 54 percent of Pseudomonas aeruginosa strains were resistant to Cefpirome, Cefepime, Ciprefloxacin and Gentamicin. 18 and 10 percent of were resistant to Meropenem and Imipenem respectively. Less than 10 percent of strains were resistant to Amikacin, Aztreonam, Piperacillin-tazobactam or Ceftazidime. Most of beta-lactam resistance of Pseudomonas aeruginosa was associated to dicreased susceptibility or resistance to Cefpirome, Cefepime or to Meropenem-Imipenem and did not match clearly with known beta-lactamase profiles. The knowledge of susceptibility of these bacteria responsible for nosocomial infections, will help to plan the appropiate use of antimicrobials