Your browser doesn't support javascript.
loading
Pharmacokinetics of oral ranitidine in Mexicans
Arch. med. res ; 27(3): 349-52, 1996. tab, ilus
Artículo en Inglés | LILACS | ID: lil-200335
RESUMO
The pharmacokinetics of oral ranitidine were studied in 24 Mexican male healthy volunteers. Subjects received a tablet containing 150 mg of ranitidine (Azantac TM, Glaxo de Mexico, Mexico, City) after an overnight fast and blood samples were drawn at several times for a period of 24 h. Ranitidine concentration in plasma was measured by high performance liquid chromatography and pharmacokinetic parameters were determined by non-compartmental analysis. Ranitide plasma concentration increased with time, reaching a maximum of (mean ñ SEM) 484 ñ 34 ng/ml in 2.7 ñ 0.2 h. Plasma levels then decayed with a terminal half-life of 4.8 ñ 0.3 h. The area under the plasma concentration against time curve was 2440 ñ 126 ngh/ml. Oral ranitidine pharmacokinetic parameters in mexicans appeared to be similar to those previously reported for caucasians
Asunto(s)
Buscar en Google
Índice: LILACS (Américas) Asunto principal: Plasma / Ranitidina / Farmacocinética / Cromatografía / Nizatidina / Cloruro de Metileno Límite: Adulto / Humanos / Masculino País/Región como asunto: México Idioma: Inglés Revista: Arch. med. res Asunto de la revista: Medicina Año: 1996 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Buscar en Google
Índice: LILACS (Américas) Asunto principal: Plasma / Ranitidina / Farmacocinética / Cromatografía / Nizatidina / Cloruro de Metileno Límite: Adulto / Humanos / Masculino País/Región como asunto: México Idioma: Inglés Revista: Arch. med. res Asunto de la revista: Medicina Año: 1996 Tipo del documento: Artículo