Age-specific prevalence of antibodies to hepatitis A in children and adolescents from Rio de Janeiro, Brazil, 1978 and 1995. Relationship of prevalence to environmental factors
Mem. Inst. Oswaldo Cruz
;
93(1): 1-5, Jan.-Feb. 1998. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-201984
RESUMO
The age-specific prevalence of antibodies to hepatitis A virus (anti-HAV) was determined in two different population groups with low socio-economic status from Rio de Janeiro city, Brazil, whose serum were collected 17 years apart (Population 1, 1978; Population 2, 1995). In Population 2, analysis of the anti-HAV prevalence was also carried out with respect to environmental factors. Population 1 was composed of 520 stored sera collected from the umbilical cord of term neonates and children aged 1 month to 6 years. In population 2, 720 serum samples were collected from children and adolescents with ages ranging from 1 to 23 years. The overall prevalence rate of anti-HAV in Population 1 and 2 was 65.6 per cent and 32.1 per cent, respectively. In Population 1, the anti-HAV prevalence reached 88 per cent at the age of 3, while in Population 2, it increased from 4.5 per cent in children under the age of 3 to 66 per cent in the group of adolescents over the age of 14. The low exposure to HAV infection in younger children from Population 2 could be a result of improved environmental hygiene and sanitation, as demonstrated by the presence of piped water, waste and sewage disposal systems in most houses from this population group. These findings indicate a possible change in the prevalence of hepatitis A in Rio de Janeiro.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Anticuerpos Antihepatitis
/
Distribución por Edad
/
Hepatitis A
Tipo de estudio:
Estudio observacional
/
Estudio de prevalencia
/
Factores de riesgo
Límite:
Adolescente
/
Niño
/
Humanos
/
Recién Nacido
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
1998
Tipo del documento:
Artículo
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