Primary growth hormone insenitivity syndrome - A review
Arq. bras. endocrinol. metab
;
41(4): 155-62, dez. 1997. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-208793
RESUMO
Primary growth hormone insensitivity produces a clinical picture of severe GH deficiency, but with elevated serum levels of GH as the result of the inability to respond normally to endogenous GH, with absence of feedback suppression of GH release. Since the original description of GH receptor deficiency by Laron and colleagues, only 230 cases have been reported. In this review the authors discuss the clinical and biochemical aspects, the molecular genetic and treatment of this syndrome.
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Índice:
LILACS (Américas)
Asunto principal:
Factor I del Crecimiento Similar a la Insulina
/
Hormona de Crecimiento Humana
Límite:
Humanos
Idioma:
Inglés
Revista:
Arq. bras. endocrinol. metab
Asunto de la revista:
Endocrinologia
/
Metabolismo
Año:
1997
Tipo del documento:
Artículo
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