CEA as a prognostic index in colorectal cancer
São Paulo med. j
;
115(6): 1589-92, nov.-dez. 1997. tab
Artículo
en Inglés
| LILACS
| ID: lil-209326
ABSTRACT
Introduction:
The carcinoembryonic antigen, CEA, is the tumor marker most used in colorectal patients, principally during follow up after radical surgery. High serum CEA level before surgery is often associated with worse prognosis, in some studies. Objetive The purpose of this study was to evaluate the preoperative carcinoembryonic antigen levels (CEA) and the frequency of recurrence. Material andMethods:
Eighty-three patients with colorectal cancer at Dukes stages A, B or C were evaluated retrospectively. The patients'follow up was at least two years or to death. CEA was determined in serum by enzyme immunoassay (Sorin Biomedica), normal value 0-5ng/ml.Results:
Disease recurrence was observed in 32 patients (38.5 percent), 13 Dukes B and 19 Dukes C. Seventy five per cent of the patients with CEA higher than 10ng/ml relapsed and 80 percent of the patients without recurrence had normal CEA. Disease recurrence in patients with preoperative elevated CEA occurred during the first year of follow up in 56 percent of the patients.Conclusion:
Although the tumor stage is today the most valuable prognostic variable in colorectal cancer, the preoperative CEA value can provide some additional information in the prognosis of the patient.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Neoplasias Colorrectales
/
Antígeno Carcinoembrionario
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Aged80
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
São Paulo med. j
Asunto de la revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Año:
1997
Tipo del documento:
Artículo
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