Genomic and phylogenetic analysis of hapatitis C virus strains from Argentina
Medicina (B.Aires)
;
58(2): 153-9, 1998. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-212787
ABSTRACT
HCV genomic characterization was performed by nucleotide sequence analysis (n=50) combined with restriction fragment length polymorphism (RFLP) of the 5'UTR region in 82 isolates coresponding to different Argentine groups. Genotype 1 was detected in 70.7 percent of the samples (58 out of 82), genotype 2 in 21.9 percent (18 of 82) and genotypes 3 in the remaining 6 sera (7.3 percent). HCV ib subtype contributed with 35.3 percent to the whole population studied (29 of 82) and was detected in 6 out of 21 sporadic cases. Besides their epidemiological significance, these results should be taken into account when future vaccines are considered on the basis of geographical HCV genotypic prevalence.
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Índice:
LILACS (Américas)
Asunto principal:
Filogenia
/
Polimorfismo de Longitud del Fragmento de Restricción
/
Hepacivirus
/
Hepatitis C Crónica
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
País/Región como asunto:
America del Sur
/
Argentina
Idioma:
Inglés
Revista:
Medicina (B.Aires)
Asunto de la revista:
Medicina
Año:
1998
Tipo del documento:
Artículo
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