Effects of massive transfusion on oxygen availability
São Paulo med. j
;
116(2): 1675-80, Mar.-Apr. 1998. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-216890
RESUMO
Objectives:
To determine oxygen derived parameters, hemodynamic and biochemical laboratory data (2,3 Diphosphoglycerate, lactate and blood gases analysis) in patients after cardiac surgery who received massive blood replacement.Design:
Prospective study.Setting:
Heart Institute (Instituto do Coraçao), Hospital das Clínicas, Faculdade de Medicina, Universidade de Sao Paulo, Brazil.Participants:
Twelve patients after cardiac surgery who received massive transfusion replacement; six of them evolved to a fatal outcome within the three-day postoperative follow-up. Measurements and MainResults:
The non-survivors group (n=6) presented high lactate levels and low P(50) levels, when compared to the survivors group (p<0.05). Both groups presented an increase in oxygen consumption and O2 extraction, and there were no significant differences between them regarding these parameters. The 2,3 DPG levels were slightly reduced in both groups.Conclusions:
This study shows that patients who are massively transfused following cardiovascular surgery present cell oxygenation disturbances probably as a result of O2 transport inadequacy.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oxígeno
/
Consumo de Oxígeno
/
Choque Hemorrágico
/
Transfusión Sanguínea
/
Ácido Láctico
/
2,3-Difosfoglicerato
/
Procedimientos Quirúrgicos Cardíacos
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
Límite:
Humanos
Idioma:
Inglés
Revista:
São Paulo med. j
Asunto de la revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Año:
1998
Tipo del documento:
Artículo
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