NGF in experimental models of parkinson disease
La Habana; s.n; 1996. 4 p. graf.
No convencional
en Inglés
| LILACS
| ID: lil-223654
ABSTRACT
We have now applied the enzyme immunoassay usin anti-NGF monoclonal antibody (MAb) 27/21 and a blocking test validating the specificity of the immunoreactivity for NGF in serum samples to examine NGF levels in normal rat sera, hemiparkinsonian rat sera, normal monkey sera, and MPTP-treated monkey sera. The levels of NGF in treated animals showed reductions when compared with serum from normal animals. The NGF level alterations observed in lesioned animals and in human parkinsonian patients evidence a relationship between this neurotrophic factor and the neurodegenerative changes observed in Parkinson disease
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Índice:
LILACS (Américas)
Asunto principal:
Enfermedad de Parkinson
/
Ratas
/
1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina
/
Sueros Inmunes
/
Factores de Crecimiento Nervioso
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Año:
1996
Tipo del documento:
No convencional
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