Validation of 14-C-urea breath test for diagnosis of Helicobacter pylori
Rev. Inst. Med. Trop. Säo Paulo
;
41(1): 3-7, Jan.-Feb. 1999. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-236718
ABSTRACT
The aim of this study was to validate the 14C-urea breath test for use in diagnosis of Helicobacter pylori infection. Thirty H. pylori positive patients, based on histologic test and thirty H. pylori negative patients by histology and anti-H. pylori IgG entered the study. Fasting patients drank 5 uCi of 14C-urea in 20 ml of water. Breath samples were collected at 0, 5, 10, 15, 20 and 30 min. The difference of cpm values between the two groups was significant at all the time intervals, besides time 0 (p<0.0001). At 20 min, the test gave 100 percent sensitivity and specificity with a cut-off value of 562 cpm. Females were higher expirers than males (p=0.005). 14C-urea breath test is highly accurate for Helicobacter pylori diagnosis. It is fast, simple and should be the non-invasive test used after treating Helicobacter pylori infection.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Ureasa
/
Pruebas Respiratorias
/
Infecciones por Helicobacter
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Asunto de la revista:
Medicina Tropical
Año:
1999
Tipo del documento:
Artículo
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