Experimental infection of canine peritoneal macrophages with visceral and dermotropic Leishmania strains
Mem. Inst. Oswaldo Cruz
;
94(5): 645-8, Sept. 1999. ilus
Artículo
en Inglés
| LILACS
| ID: lil-241325
RESUMO
A study was carried out using macrophages cultured from the peritoneal exudate of dogs infected in vitro with three species of Leishmania L. (L.) chagasi, L. (Viannia) braziliensis and L. (L.) amazonensis with the aim of investigating the growth kinetics and infectivity of these species in the host cell. Results were expressed as the percentage of macrophages infected measured at 24 hr intervals over six days in RPMI - 1640 culture medium at a temperature of 34-35oC. The findings open the possibility of using canine peritoneal cells as a model for the screenning of leishmanicide drugs and to study the pathogenesis of these species.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Técnicas In Vitro
/
Macrófagos Peritoneales
/
Leishmania
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
1999
Tipo del documento:
Artículo
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