Olive oil protects against chromosomal aberrations induced by doxorubicin in wistar rat bone marrow cells
Genet. mol. biol
;
22(2): 225-7, jun. 1999. tab
Artículo
en Inglés
| LILACS
| ID: lil-242205
RESUMO
There is considerable interest in identifying dietary compounds which have the capacity to protect against chromosomal aberrations induced by antitumor agents. Fatty acids and their constituents are able to act as free radical scavengers. Doxorubicin (DXR) is an important chemotherapeutic agent, that also induces chromosome aberrations. Rat bone marrow cells treated simultaneously with olive oil (10 ml/kg body weight) and DXR (90 mg/kg body weight) developed significantly fewer chromosomal aberrations and abnormal metaphases than those treated with DXR alone.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Aceites de Plantas
/
Células de la Médula Ósea
/
Doxorrubicina
/
Aberraciones Cromosómicas
/
Antineoplásicos
Límite:
Animales
Idioma:
Inglés
Revista:
Genet. mol. biol
Asunto de la revista:
Genética
Año:
1999
Tipo del documento:
Artículo
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