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Estado inmunitario de 4 grupos de edad de población chilena contra sarampión y rubeola / Immune status against measles and rubella among chilean subjects of different ages
Valenzuela B., M. Teresa; Vega Morales, Jeanette; Leal S., Irene; Vicente Suárez, Manuela; Young P., Verónica; Vera M., Lilian; Fasce P., Rodrigo; Ramírez V., Eugenio.
Afiliación
  • Valenzuela B., M. Teresa; s.af
  • Vega Morales, Jeanette; s.af
  • Leal S., Irene; s.af
  • Vicente Suárez, Manuela; s.af
  • Young P., Verónica; s.af
  • Vera M., Lilian; s.af
  • Fasce P., Rodrigo; s.af
  • Ramírez V., Eugenio; s.af
Rev. méd. Chile ; 127(3): 359-65, mar. 1999. tab, graf
Article en Es | LILACS | ID: lil-243803
Biblioteca responsable: CL1.1
RESUMO

Background:

Results of clinical and epidemiological studies confirm that no cases of measles have occurred in Chile since 1993. However, since covering of vaccination programs do not exceed 95 percent, an immunological surveillance for this disease is warranted.

Aim:

To know the immune status against measles and rubella in the Chilean population. Material and

methods:

A serological census of a representative sample of communities with high (90 percent or more) or low immunization coverings was performed. Four sub samples along the country were selected 122 children aged 18 months of age (stratum A), 1,276 children attending the first year of basic school (stratum B), 899 teenagers in their last high school year (stratum C) and 399 women attending a family planning clinic (stratum D). IgG antibodies against measles and rubella were measured using ELISA and hemagglutination inhibition techniques, respectively.

Results:

Antibodies against measles and rubella were found in 96 percent and 94 percent of study subjects. No differences in these titres were found between different strata or communities with high or low vaccination covering. There is a high percentage of positive antibodies against measles among children of 18 months of age and a high percentage of antibodies against rubella among teenagers and women in family planning. Only 3 percent of the sample had not received any vaccine at the moment of the study.

Conclusions:

The high prevalence of antibodies against rubella allows to conclude that it is not necessary to consider this antigen in the next vaccination campaign. Due to the high prevalence of antibodies against measles, only the population older than 20 years old should be affected by the disease if this virus enters the country
Asunto(s)
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Índice: LILACS Asunto principal: Rubéola (Sarampión Alemán) / Sarampión / Anticuerpos Antivirales Tipo de estudio: Risk_factors_studies Límite: Adolescent / Adult / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do sul / Chile Idioma: Es Revista: Rev. méd. Chile Asunto de la revista: MEDICINA Año: 1999 Tipo del documento: Article
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Índice: LILACS Asunto principal: Rubéola (Sarampión Alemán) / Sarampión / Anticuerpos Antivirales Tipo de estudio: Risk_factors_studies Límite: Adolescent / Adult / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do sul / Chile Idioma: Es Revista: Rev. méd. Chile Asunto de la revista: MEDICINA Año: 1999 Tipo del documento: Article