Prospective evaluation of in vitro prodution of HIV-1 specific antibodies (IVAP), p24 antigenemia and viral culture for the diagnosis of HIV infection in children born to HIV-1 infected mothers
Braz. j. infect. dis
;
1(3): 131-4, Jun. 1997. tab
Artículo
en Inglés
| LILACS
| ID: lil-247328
RESUMO
Three methods (IVAP, p24 antigenemia and viral cultivatio) for the diagnosis of HIV-1 infection among children born to HIV-1 infected mothers were prospectively evaluated to determine the applicability of IVAP as a useful technique for that purpose. We tested 15 children (8p0 and 7 pII) and 19 adults with well-estabilished serological status for HIV infection. The children were followed for at least 1 year, unless they developed symptoms of clinical AIDS, or their HIV serology became negative. The IVAP method was more sensitive and specific than the other 2 tests in determining whether or not the infants were infected with HIV. All negative test results (5/8) were confirmed during the same time period. Despite the small sample studied, we conclude that IVAP is in inexpensive and simple technique potentially useful to establish whether or not HIV-seropositive children born to infected mothers are HIV infected.
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Índice:
LILACS (Américas)
Asunto principal:
Cultivo de Virus
/
Técnicas In Vitro
/
Serodiagnóstico del SIDA
/
Anticuerpos Anti-VIH
/
Infecciones por VIH
/
Reacción en Cadena de la Polimerasa
/
VIH-1
/
Transmisión Vertical de Enfermedad Infecciosa
/
Formación de Anticuerpos
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Lactante
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
1997
Tipo del documento:
Artículo
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